Literature ReviewMonnet et al(1) published a review article on the assessment of volume responsiveness in mechanically ventilated patients using heart-lung interactions. He explained that mechanical ventilation produces cyclic changes in left ventricular stroke volume due to inspiration- and expiration-induced changes in left ventricular preload. Denotes the preload dependence of the left ventricle indirectly on the right ventricle. It also describes various limitations of respiratory changes in SV to predict fluid responsiveness. Guidet et al(2) conducted a study on patients with sepsis to find efficacy and hemodynamic safety between 6% HES 130/0.4 vs 0.9% NaCl. It found that volume requirements were lower with HES than with NaCl in the initial phase of fluid resuscitation, and the time to achieve hemodynamic stability was also shorter with HES. There was no difference between the AKIN and RIFLE criteria between the two groups. Furthermore, no difference in mortality was found up to 90 days after resuscitation. Christoph K Hofer et al(3) performed a study to identify which system best predicted fluid responsiveness between the FloTrac/Vigileo and the PiCCO plus system, using stroke volume variation (SVV) as a predictor of fluid responsiveness. The study was conducted in patients undergoing elective cardiac surgery. He used a method to induce volume shift by changing the body position from 30° head-up to 30° head-down. SVV was determined using the Flotrac radial sensor and the PiCCO plus femoral catheter. The decrease in SVVs detected using Flotrac and PiCCO plus was significant and the correlation between the two SVVs was also significant. It also found that SVV measured using FloTrac has a lower prediction threshold than the others. Jan Be...... middle of paper ......sided. Through a subcostal approach, the diameter of the IVC was measured at the end of inspiration (D max) and at the end of expiration (D min) using echocardiography and the distensibility index was calculated (dIVC=Dmax-Dmin/ Dmin). Cardiac index (CI) measured using the Doppler technique in the pulmonary arterial trunk. Patients showing a 15% increase in CI after volume infusion with 7 ml/kg plasma expanders were designated as responders. A strong relationship (r = 0.9) was observed between baseline dIVC and increased CI following blood volume expansion. Stawiki SP(11) et al performed a study to compare USG-guided assessment of inferior vena cava collapsibility index (IVC-CI) and central venous pressure. He found an inverse relationship between CVP and IVC-CI. An IVC-CI less than 25% is consistent with euvolemia or hypervolemia, while an IVC-CI greater than 75% suggests intravascular volume depletion.