Climate change is causing Earth to readjust. The polar ice caps are melting, lakes are evaporating, droughts are occurring, and the planet as a whole is warming. This is changing even small things like microbes. Microbes live in every corner of this planet. Some are beneficial to life, however many are disease-causing pathogens resulting in loss of some bodily functions or even life. Countless pathogens are affected by climate change, but one particularly affected is N. fowleri. The relationship between Naegleria fowleri and humans has been altered by climate change resulting in geographic spread, increased infection rates, and a longer lifespan for the pathogen. Naegleria fowleri is a single-celled protozoan pathogen found in fresh water bodies and soil worldwide (Skurie; Byrd 8). It thrives in the sediment layer at the bottom of lakes and ponds. (Skurie). When living in soil, N. fowleri, along with other protozoan microbes, clings to plant roots in search of bacteria (Byrd 261). This pathogen is a free-living pathogen classified as an amphizoan amoeba, therefore it survives in the free state in soil and freshwater while having the capacity to be a pathogen (Marciano-Cabral, “Immune”). It primarily searches for bacteria due to the inability to create food (Byrd 27); however, N. fowleri will attack a host if given the opportunity. Furthermore, it has been shown that brain pathogens are often able to control the actions of their host to better meet the needs of the pathogen. An example would be causing the host to have a high body temperature, wanting to stay warmer or sleep more often (Byrd 225). This microbe is typically found as a trophozoite, cyst, or... middle of paper... mate switching is becoming a catalyst for Naegleria fowleri and PAM infections. The pathogen is forced to readapt for a warmer Earth. As a result, N. fowleri is beginning to spread into fresh bodies of water in northern states where it previously would not have been able to survive. It also gives N. fowleri a larger window of time to proliferate and obtain a host to attack, which could result in more infections globally. Although scientists and doctors try to find cures and vaccinations for the pathogen, they are yet to find an inclusive solution to work on all infections. Climate change is causing major changes in the amoeba Naegleria fowleri. Therefore, the relationship between Naegleria fowleri and humans is being altered by climate change resulting in geographic spread, increased infection rates, and a longer lifespan for the pathogen..