To many, prokaryotes may seem like uninteresting and insignificant organisms, but to biologists, prokaryotes have the greatest success story in the history of life. Prokaryotes have existed for at least 3.5 billion years, considering that the earth is more than 4.5 billion years old. They are the first known organisms to inhabit the earth. They may still seem small and insignificant, but they are able to endure and evolve on their own for over 2 billion years. They have made a substantial impact on all life we ​​know of on earth and have been able to survive and adapt to an ever-changing earth. Although there are many differences between prokaryotic cells and eukaryotic cells. Nonetheless, it is their similarities that scientists have found intriguing and that have led to speculation about the origin of life, but have been overlooked by other scientists for nearly a century. Although prokaryotic and eukaryotic cells have existed for billions of years, it was not until 1883 when the first observations of a symbiotic union of organisms were formed. The French botanist Andreas Franz Schimper (1856-1901) could observe the similarities in cell division of that of free-living cyanobacteria and chloroplasts. It was his studies on the potential endosymbiotic nature of cells that led him to theorize the evolution of green plants. In 1905, another biologist Konstantin Mereschkowsky (1855-1921) was the first to develop the idea of ​​symbiogenesis which implies that symbiosis is "...middle of paper...transfer of genes between organisms occurs which is beneficial to both the host cell and the symbiont. investigation at the University of Miami established that an animal A cell and a symbiotic bacterium can come together to create a single organismal system. One of their experiments involved the pea aphid which would have governed the production of essential nutrients that its symbiotic bacterium, Buchnera aphidicola, would have provided. All in all we are able to understand the significance of prokaryotes, not only for the human species, but also for other species and organisms These prokaryotes are the inventors of biochemical pathways and contain extreme biochemical diversity that has allowed them to survive and succeed as a kingdom in their own right...